NETs: Custom capture technology

 

NETs are an advanced capture platform that enables rapid capture and detection of multiple targets of interest in remarkably small sample volumes. As seen in the micro-scale image on the left, our NETs utilize a unique 3-D scaffold to bind targets of interest with exceptional yield and specificity, while avoiding unwanted contamination. NETs are adaptable for single- or multi-target evaluation of virtually any molecule or even cell type of interest, often surpassing sensitivities of pre-existing assays to the femto-molar range. The technology is compatible with a wide variety of downstream applications, and raw sample compatibility allows for sample prep times of less than 30 minutes.

The NETs advantage

Efficiency


NETs technology benefits from unparalleled capture and detection sensitivities, combined with minimized non-specific binding. Sample prep times are typically 30-45 minutes from raw sample to answer.

Conventional Capture Methods

  • Capture 1 target of interest
  • Low capture yield per bead
  • High non-specific binding
  • Extensive sample prep time

NETs

  • Simultaneous capture of multiple targets of interest
  • Maximum binding capacity per bead
  • 30-45 minute sample-to-result
  • Point-of-Care enabling

Customizability


NETs are highly customizable to bind and extract a wide variety of cellular and molecular targets from almost any sample type.

Compatible Samples

Clinical Targets

  • Whole Blood
  • Plasma
  • Serum
  • Saliva
  • Nasal Swabs
  • Throat Swabs
  • Skin Swabs
  • Feces
  • Cells
  • Protein
  • Nucleic Acid
  • Lipids
  • Whole Virus
  • Carbohydrates
  • Vesicles
  • Small Molecules

Flexibility


Once target(s) are captured, NETs remain compatible with a variety of downstream clinical, R&D and industrial applications.

Clinical Test Applications

  • FACS
  • FISH
  • Next Gen Sequencing
  • Cellular Activity Assays
  • ELISA
  • PCR (q & qRT)
  • Mass Spectrometry
  • Luminex
  • Fluorimetry
  • Colorimetric Assays
  • Fluorescent Microscopy
  • Plasmon Resonance
 

Compatible targets include many that are key biomarkers in cutting-edge diagnostic tests such as exosomes, cells, proteins, nucleic acids and lipids. - Dr Emily Stein

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